O Brien Vacation Packages 2026 from $462

O Brien flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

Econo Lodge Jennings

$462

per person

Oct 2 - Oct 4

found 1 day ago

Roundtrip non-stop flight included

Dallas (DFW) to Gainesville (GNV)

This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. A picnic area is also provided.

Howard Johnson by Wyndham Ocala FL I-75

$636

per person

Oct 8 - Oct 12

found 6 hours ago

Roundtrip non-stop flight included

Chicago (ORD) to Gainesville (GNV)

This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. Relax with a drink at the bar/lounge and enjoy free perks like continental breakfast and free self parking.

Jasper Sunshine Getaway

$726

per person

Oct 15 - Oct 18

found 1 day ago

Roundtrip flight included

Dallas (DFW) to Gainesville (GNV)

This vacation home doesn't skimp on freebies - guests receive free WiFi and free self parking. A garden and barbecue grills are also provided.

Top O Brien hotels deals

MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY

O'Brien FL

$356 nightly

$387 total

Aug 25 - Aug 26

Total with taxes and fees

A garden, express check-in, and express check-out are available at this vacation home. Laundry facilities and barbecue grills are also provided.

Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!

obrien FL

Get rates

A gym is featured at this vacation home, along with a garden and laundry facilities. There's fun for all ages with a playground and an arcade/game room, and barbecue grills are available on site.

Best Western Plus Lake City

350 SW Florida Gateway Dr Lake City FL

Free Cancellation

Reserve now, pay when you stay

$81 nightly

$91 total

Sep 7 - Sep 8

Total with taxes and fees

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

16367 NW 167TH BLVD Alachua FL

Free Cancellation

$92 nightly

$104 total

Sep 21 - Sep 22

Total with taxes and fees

This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and free perks like buffet breakfast and free self parking.

La Quinta Inn & Suite by Wyndham Lake City

165NW CALI DRIVE Lake City FL

Free Cancellation

Reserve now, pay when you stay

$90 nightly

$101 total

Aug 30 - Aug 31

Total with taxes and fees

This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like on-the-go breakfast and free self parking.

Comfort Suites Lake City

3690 W Us Highway 90 Lake City FL

Free Cancellation

$93 nightly

$104 total

Aug 31 - Sep 1

Total with taxes and fees

This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much are vacation packages to O Brien?

$462 is all you need to spend for a memorable vacation in O Brien. Bundle your flights and hotel into a vacation package with Travelocity and see the savings add up. With prices this good, you'll want to start packing your suitcase now!

How long should my O Brien vacation be?

Many travelers choose to spend about 5 nights in O Brien. But that's only a guide. Whether you prefer to stay for a couple of days or a couple of weeks, you'll love exploring all the amazing things that this destination has to offer.

Where can I get the best vacation package deals for O Brien?

You'll come across an amazing range of O Brien package deals on Travelocity. With 400 airlines and 1,000,000 properties across the globe, organizing your dream vacation will be easy.

Why should I purchase my O Brien vacation package with Travelocity?

Because life is all about the journey, and we have everything you need to help you on your way. With our excellent service and Price Match Guarantee, you can organize your trip with confidence. What's more, you can rest easy on the road knowing you can reach us with our round-the-clock support.

Can I save on my O Brien car rental if I combine it with my hotel or flight?

With an O Brien vacation package, you can combine your hotel, flight and car bookings and save a ton. If you're in the mood to discover the best of this fantastic region, why not start with University of Florida? This renowned attraction is 45 mi from O Brien. With your own rental car, you'll be there in no time.

Which airport is best for O Brien?

One of your top options is Gainesville Regional Airport (GNV), which you'll find 45 mi southeast of downtown O Brien. Your other choice is Valdosta Regional Airport (VLD), 55 mi away from central O Brien).

Where should I stay when visiting O Brien?

Many people opt to check in to the Pet-Friendly Florida Escape w/ Patio & Fire Pit!. It's a terrific base for your O Brien getaway.